STAT+: A Novartis drug cut inflammation. Can it improve heart outcomes?
A newly acquired Novartis drug successfully lowered signs of inflammation in a midstage study, as experts wait to hear how the company plans to advance the drug as a potential cardiovascular treatment.…
In the Phase 2 TRANQUILITY study, the drug, pacibekitug, led to sustai…
Investigators reported a dose-dependent drop in biomarker levels on ce…
Pacibekitug is an antibody that targets IL-6, or interleukin-6, a prot…
Juul gets OK to sell updated vaping device with age-gating technology
WASHINGTON — Vaping company Juul Labs on Friday received federal permission to sell an updated version of its e-cigarette, which includes an optional age-verification system designed to prevent underage use.…
The decision from the Food and Drug Administration allows the company …
In recent years, the company has had to lay off hundreds of employees …
Opinion: The unintended consequences of the Lindsay Clancy case
Much of the focus on the Lindsay Clancy case has been on the reported systemic failures of the mental health system, with the hope that this case will revamp the approach to maternal mental health.…
We, as forensic and reproductive psychiatrists, agree that the system …
But we are concerned that this focus could have a dangerous unintended…
In an ideal world, all mothers would have easy access to reproductive …
STAT+: Pharmalittle: We’re reading about an AstraZeneca trial failure, a ‘monstrous’ conflict of interest, and more
And so, another working week will soon come to a close.Not a moment too soon, yes?This is, you may recall, our treasured signal to daydream about weekend plans.…
Our agenda is still taking shape, but we plan on promenading with the …
Pharmalot to a speakeasy and, if time permits, holding another listeni…
STAT+: In autopsy of failed heart disease study, AstraZeneca raises broader questions about silencer drugs
AstraZeneca on Friday detailed the surprise failure of a closely watched heart disease clinical trial, laying out how its experimental drug offered no additional benefits for patients who were largely already on another type of medicine — the latest twist in a multi-billion dollar market.…
The study indicated that patients with a progressive condition known a…
Most participants were on a stabilizer at the outset of the trial.
The trial’s miss has had implications not just for AstraZeneca and its…
STAT+: Vaccines take center stage at federal autism advisory committee
Vaccines took center stage at the federal autism advisory committee meeting Thursday, as committee members explicitly pointed to vaccines as a potential cause of autism, even though the link has been routinely debunked.…
“We don’t want to close the door for any potential trigger, and that w…
“We are quite open to investigating anything and everything.
STAT+: FDA approves Roivant therapy for rare autoimmune disease
The Food and Drug Administration on Thursday approved a new medicine from Roivant and its subsidiary Priovant for the treatment of dermatomyositis, a rare autoimmune disease characterized by muscle weakness and a painful skin rash.…
The drug, called brepocitinib, will be marketed under the brand name L…
It’s a pill taken once daily.
High doses of steroids and other immune-suppressing drugs are the curr…
STAT+: Former Stanford president releases emails to rebut fraud and cover-up allegations in new book
Three years after a closely watched research misconduct investigation of Stanford’s then-president, Marc Tessier-Lavigne, led to his resignation, the prominent neuroscientist revealed new details this week from his research and travel in an attempt to refute allegations that he published fraudulent results and orchestrated a cover-up.…
These allegations found new life this year with the release of “How to…
A key part of that story revolves around a major paper on neurodegener…
The former university head on Wednesday posted a more than 3,000-word …
STAT+: Alnylam’s heart drug troubles take center stage at a cardiology conference
This story first appeared in Adam’s Biotech Scorecard, a subscriber-only newsletter.STAT+ subscribers can sign up here to get it delivered to their inbox.…
The European Society of Cardiology Congress that kicks off Friday in M…
Cardiologists and investors attending the ESC meeting will learn new d…
Opinion: I studied Reddit forums on menopause — and found what doctors are missing
In forums on Reddit, women share tales of having perimenopause and menopause symptoms misdiagnosed or dismissed as mental health disorders, early-onset dementia, or autoimmune issues, resulting in months or years of unnecessary testing.…
They discuss sudden mood shifts of rage, and panic, and how they are r…
Severe brain fog, memory lapses, and sleeplessness from night sweats —…
Opinion: STAT+: A bill is supposed to protect U.S. biotech from Chinese competition. But there’s a loophole
Bipartisan legislation under review in Congress has the potential to significantly rejigger global drug development — and the biggest beneficiaries may not be American.…
The bill, titled the Biotech Investment National Security Act (BINSA),…
The policy is an add-on to the restrictions of the Comprehensive Outbo…
BINSA’s sponsors frame the additional policy as necessary to protect U.